| 货号 | 3941/50 |
| 别名 | 5-Nitro-α-oxo-N-(1R)-phenylethyl]-1H |
| 供应商 | Tocris |
| 生物活性 | GABAAα2 agonist and GABAAα1 partial agonist in vitro(Ki values are 14 and 121 nM respectively). Exhibits non-sedative anxiolytic activity in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 337.33 |
| 分子式 | C18H15N3O4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 355022-97-8 |
| 参考文献 | Talianiet al (2009) Identification of anxiolytic/nonsedative agents among indol-3-ylglyoxylamides acting as functionally selective agonists at the γ-aminobutyric acid-A (GABAA) κ2 benzodiazepine receptor. J.Med.Chem. 52 3723. PMID: 19469479. Primofioreet al (2001) Novel N-(arylalkyl)indol-3-ylglyoxylamides targeted as ligands of the benzodiazepine receptor: synthesis, biological evaluation, and molecular modeling analysis of the structure-activity relationships. J.Med.Chem. 44 2286. PMID: 11428922. |