SU 3327 (50 MG)
货号：
3607/50 基本售价：
9894.7 元 规格：
50 mg
产品信息
概述| 货号 | 3607/50 |
| 别名 | 5-[(5-Nitro-2-thiazolyl)thio]-1,3,4thiadiazol-2-amine |
性能| 供应商 | Tocris |
| 生物活性 | Selective inhibitor of c-Jun N-terminal kinase (JNK) (IC50 = 0.7 μM). Inhibits the protein-protein interaction between JNK and JIP (IC50 = 239 nM). Displays selectivity over p38 MAPK and Akt. Restores insulin sensitivity in a mouse model of type-2 diabetes. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 261.3 |
| 分子式 | C5H3N5O2S3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
| CAS号 | 40045-50-9 |
| 参考文献 | Deet al (2009) Design, synthesis and structure-activity relationship of substrate competitive, selective, and in vivo active triazole and thiadiazole inhibitors of the c-jun N-terminal kinase. J.Med.Chem. 52 1943. PMID: 19271755. |
