货号 | 1148/50 |
别名 | N-Cyano-N'-methyl-N''-[4-(1,4,5,6-tetr |
供应商 | Tocris |
生物活性 | Phosphodiesterase inhibitor, selective for PDE3 (IC50 = 117 nM). |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 284.32 |
分子式 | C14H16N6O |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
CAS号 | 115344-47-3 |
参考文献 | Freitaget al (1998) Phosphodiesterase inhibitors suppress α2-adrenoceptor-mediated 5-hydroxytryptamine release from trachea of newborn rabbits. Eur.J.Pharmacol. 354 67. PMID: 9726632. Christensen and Torphy (1994) Isozyme-selective phosphodiesterase inhibitors as antiasthmatic agents. Annu.Rep.Med.Chem. 29185. Tanget al (1994) Photoaffinity labelling of cyclic GMP-inhibited phosphodiesterase (PDE III) in human and rat platelets and rat tissues: effects of phosphodiesterase inhibitors. Eur.J.Pharmacol. 268 105. PMID: 7925608. |