| 货号 | 4752/50 |
| 别名 | 4-[2-(4-Chlorophenyl)ethyl]-1-piper |
| 供应商 | Tocris |
| 生物活性 | Potent inhibitor of fatty acid amide hydrolase (FAAH) (IC50 <10 nM). Also inhibits MAGL at higher concentrations (IC50 values are 410 nM and 1.4 μM respectively). Inhibits both human and mouse FAAH enzymes. Exhibits inhibitory activity against FAAH, MAGL and ABHD6 in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 338.83 |
| 分子式 | C17H23ClN2O3 |
| 可溶性/溶解性 | Soluble to 25 mM in DMSO and to 20 mM in ethanol |
| 参考文献 | Owenset al (2016) Discriminative stimulus properties of the endocannabinoid catabolic enzyme inhibitor SA-57 in mice. J.Pharmacol.Exp.Ther 358 306. PMID: 27307500. Niphakiset al (2012) O-hydroxyacetamide carbamates as a highly potent and selective class of endocannabinoid hydrolase inhibitors. ACS Chem.Neurosci. 3 418. PMID: 22860211. |