货号 | 3828/50 |
别名 | 1-[(2,6-Difluorophenyl)methyl]-1H-1 |
供应商 | Tocris |
生物活性 | Board spectrum anticonvulsant. Prolongs the inactivation of sodium channels and limits the frequency of action potential firing in cultured and acutely isolated neurons. Displays anticonvulsive activity in a range of animal seizure models. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 238.19 |
分子式 | C10H8F2N4O |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
CAS号 | 106308-44-5 |
参考文献 | Whiteet al (2008) The anticonvulsant profile of rufinamide (CGP 33101) in rodent seizure models. Epilepsia 49 1213. PMID: 18325020. Arroyo (2007) Rufinamide. Neurotherapeutics 4 155. PMID: 17199032. Rogawskiet al (2006) Diverse mechanisms of antiepileptic drugs in the development pipeline. Epilepsy Res. 69 273. PMID: 16621450. |