| 货号 | 0991/50 |
| 别名 | 1-[4-Amino-5-chloro-2-(3,5-dimethox |
| 供应商 | Tocris |
| 生物活性 | A potent and selective 5-HT4 antagonist, with a pKi of 9.1 at 5-HT4 receptors in guinea pig striatal membranes and greater than 1000-fold selectivity over 5-HT1A, 2C, 3 and D1, D2, M1, M2, AT1,B1andα1C receptors. The ketone group gives RS 39604 a relatively long half life; it is also orally active and so suitable for in vivostudies. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 590.56 |
| 分子式 | C26H36ClN3O6S.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 167710-87-4 |
| 参考文献 | Eglenet al (1995) Central 5-HT4 receptors TiPS 16 391. PMID: 8578609. Hegde (1995) RS 39604: a potent, selective and orally active 5-HT4 receptor antagonist. Br.J.Pharmacol. 115 1087. PMID: 7582507. |