| 货号 | 2911/50 |
| 别名 | 4-Amino-N-[2,6-bis(methylamino)-4-p |
| 供应商 | Tocris |
| 生物活性 | Potent and selective 5-HT6 receptor antagonist (pKi values are 7.26 and 7.35 at rat and human 5-HT6 receptors respectively). Displays no affinity at a range of other receptors (IC50 > 10 μM). Induces stretching behavior in rats in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 308.36 |
| 分子式 | C12H16N6O2S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 202466-68-0 |
| 参考文献 | Fone (2008) An update on the role of the 5-hydroxytryptamine6 receptor in cognitive function. Neuropharmacology 55 1015. PMID: 18655798. Bentleyet al (1999) Investigation of stretching behaviour induced by the selective 5-HT6 receptor antagonist, Ro 04-6790, in rats. Br.J.Pharmacol. 126 1537. PMID: 10323584. Sleightet al (1998) Characterization of Ro 04-6790 and Ro 63-2563: potent and selective antagonists at human and rat 5-HT6 receptors. Br.J.Pharmacol. 124 556. PMID: 9647481. |