| 货号 | 4029/50 |
| 别名 | (2S)-2-[[[4-[(2-Fluorophenyl)methox |
| 供应商 | Tocris |
| 生物活性 | Sodium channel blocker. Suppresses tetrodotoxin (TTX)-resistant Na+ currents approximately twice as selectively as TTX-sensitive currents. Antinociceptive; displays analgesic effects in animal models of inflammatory and neuropathic pain. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 398.45 |
| 分子式 | C17H19FN2O2< |
| 可溶性/溶解性 | Soluble to 25 mM in water and to 100 mM in DMSO |
| 参考文献 | Zhanget al (2008) Ralfinamide administered orally before hindpaw neurectomy or postoperatively provided long-lasting suppression of spontaneous neuropathic pain-related behavior in the rat. Pain 139 293. PMID: 18583049. Yamaneet al (2007) Effects of ralfinamide, a Na+ channel blocker, on firing properties of nociceptive dorsal root ganglion neurons of adult rats. Exp.Neurol. 208 63. PMID: 17707373. Veneroniet al (2003) Anti-allodynic effect of NW-1029, a novel Na+ channel blocker, in experimental animal models of inflammatory and neuropathic pain. Pain 102 17. PMID: 12620593. |