| 货号 | 3298/50 |
| 别名 | 2-[4-[(2-Phenyl-1H-imidazol-5-yl)me |
| 供应商 | Tocris |
| 生物活性 | High affinity D4 receptor ligand; selective over D1, D2, D3 and D5 receptors. Displays antagonist activity at the human D4.2 receptor (Ki = 3.6 nM in transfected CHO cells) and exhibits agonist activity at the D4.4 receptor in HEK 293 cells. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 320.39 |
| 分子式 | C18H20N6 |
| 可溶性/溶解性 | Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO |
| CAS号 | 179333-18-7 |
| 参考文献 | Gaziet al (1999) NGD 94-1 as an agonist at human recombinant dopamine D4.4 receptors expressed in HEK293 cells. Eur.J.Pharmacol. 372 R9. PMID: 10395031. Primuset al (1997) II. Localization and characterization of dopamine D4 binding sites in rat and human brain by use of the novel, D4 receptor-selective ligand [3H]NGD 94-1. J.Pharmacol.Exp.Ther. 282 1020. PMID: 9262371. Tallmanet al (1997) I. NGD 94-1: Identification of a novel, high affinity antagonist at the human dopamine D4 receptor. J.Pharmacol.Exp.Ther. 282 1011. PMID: 9262370. |