ML 213 (50 MG)
货号：
4519/50 基本售价：
9894.7 元 规格：
50 mg
产品信息
概述| 货号 | 4519/50 |
| 别名 | N-(2,4,6-Trimethylphenyl)-bicyclo[2.2.1]heptane-2-carboxamide |
性能| 供应商 | Tocris |
| 生物活性 | Selective KV7.2 (KCNQ2) and KV7.4 (KCNQ4) channel opener (EC50 values are 230 and 510 nM for KV7.2 and KV7.4 respectively). Displays > 80-fold selectivity against KV7.1, KV7.3 and KV7.5 in a thallium-based fluorescence assay. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 257.37 |
| 分子式 | C17H23NO |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO and to 50 mM in ethanol |
| 参考文献 | Yuet al (2011) Discovery, synthesis, and structure activity relationship of a series of N-aryl-bicyclo[2.2.1]heptane-2-carboxamides: Characterization of ML213 as a novel KCNQ2 and KCNQ4 potassium channel opener. ACS Chem.Neurosci. 2 572. PMID: 22125664. |
