| 货号 | 0681/50 |
| 别名 | [1-(4-Hydroxyphenoxy)ethylidene]bis |
| 供应商 | Tocris |
| 生物活性 | A potent inhibitor of inositol monophophatase; stable to hydrolysis. Induces autophagy in COS-7 cells independently of mTOR inhibition. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 298.13 |
| 分子式 | C8H12O8P2 |
| 可溶性/溶解性 | Soluble to 100 mM in water with gentle warming |
| CAS号 | 142523-38-4 |
| 参考文献 | Fleminget al (2011) Chemical modulators of autophagy as biological probes and potential therapeutics. Nat.Chem.Biol. 7 9. PMID: 21164513. Sarkaret al (2005) Lithium induces autophagy by inhibiting inositol monophosphatase. J.Cell.Biol. 170 1101. PMID: 16186256. Atacket al (1994) Effects of L-690,488, a pro-drug of the bisphosphonate inisotol monophosphatase inhibitor L-690,330, on phosphatidylinisotol cycle markers. J.Pharmacol.Exp.Ther. 270 70. PMID: 8035344. Atacket al(1993)In vitroandin vivo inhibition of inositol monophosphatase by the bisphosphonate L-690,330. J.Neurochem. 60 652. PMID: 8380439. |