ITX 3 (50 MG)
货号:
3792/50 基本售价:
9894.7 元 规格:
50 mg
产品信息
概述货号 | 3792/50 |
别名 | (E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one |
性能供应商 | Tocris |
生物活性 | Selective inhibitor of TrioN RhoGEF activity. Inhibits TrioN-mediated GTP exchange on RhoG and Rac1, formation of TrioN-induced cellular structures in REF52 fibroblasts and NGF-mediated neurite outgrowth in PC12 cells in vitro. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 371.45 |
分子式 | C22H17N3OS |
可溶性/溶解性 | Soluble to 5 mM in DMSO |
CAS号 | 347323-96-0 |
参考文献 | Bouquieret al (2009) A cell active chemical GEF inhibitor selectively targets the Trio/RhoG/Rac1 signaling pathway. Chem.Biol. 16 657. PMID: 19549603. |