| 货号 | 5147/50 |
| 别名 | 8-[(1E)-2-(2-(3,4-Dimethoxyphenyl)e |
| 供应商 | Tocris |
| 生物活性 | Potent and selective adenosine A2A receptor antagonist (Ki values are 2.2 and 150 nM for A2A and A1 receptors respectively). Anticataleptic and antiparkinson agent; reverses drug-induced motor dysfunction in animal models. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 384.43 |
| 分子式 | C20H24N4O4 |
| 可溶性/溶解性 | Soluble to 20 mM in DMSO |
| 参考文献 | Shiozakiet al (1999) Actions of adenosine A2A receptor antagonist KW-6002 on drug-induced catalepsy and hypokinesia caused by reserpine or MPTP. Psychopharmacology 147 90. PMID: 10591873. Kandaet al (1998) Adenosine A2A receptors modify motor function in MPTP-treated common marmosets. Neuroreport 9 2857. PMID: 9760134. Shimadaet al (1997) Adenosine A2A antagonists with potent anti-cataleptic activity. Bioorg.Med.Chem.Lett. 72349. |