| 货号 | 0932/50 |
| 别名 | 4-(1H-Imidazol-4-ylmethyl)piperidin |
| 供应商 | Tocris |
| 生物活性 | Potent histamine H3 receptor agonist. Also binds to H4 receptors (Ki values are 0.4 and 9 nM at human recombinant H3 and H4 receptors respectively). Equipotent to or slightly more active than (R)-α-methylhistamine at H3receptors. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 327.06 |
| 分子式 | C9H15N3.2HBr |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 164391-47-3 |
| 参考文献 | Liuet al (2001) Cloning and pharmacological characterization of a fourth histamine receptor (H4) expressed in bone marrow. Mol. Pharmacol. 59 420. PMID: 11179434. Coruzziet al (1995) Cardiovascular effects of selective agonists and antagonists of histamine H3 receptors in the anaesthetized rat. Naunyn Schmiedebergs Arch.Pharmacol. 351 569. PMID: 7675114. Vollingaet al (1994) A new potent and selective histamine H3 receptor agonist. J.Med.Chem. 37 332. PMID: 8308858. |