| 货号 | 1483/50 |
| 别名 | 4-[(3,4-Dichlorophenyl)acetyl]-3-(1 |
| 供应商 | Tocris |
| 生物活性 | Highly potent and selective κ-opioid agonist (IC50 = 0.04 nM) that may be selective for the putative κ2 receptor. Anti-nociceptive and neuroprotective in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 530.4 |
| 分子式 | C19H25Cl2N3O3.C4H4O4 |
| 可溶性/溶解性 | Soluble to 25 mM in water with gentle warming and to 100 mM in DMSO |
| CAS号 | 126766-32-3 |
| 参考文献 | Butelmanet al (2001) GR89,696: a potent κ-opioid agonist with subtype selectivity in rhesus monkeys. J.Pharmacol.Exp.Ther. 298 1049. PMID: 11504802. Nayloret al (1993) A potent new class of κ-receptor agonist: 4-substituted 1-(arylacetyl)-2-[(dialkylamino)methyl]piperazines. J.Med.Chem. 36 2075. PMID: 8393489. Birchet al (1991) Neuroprotective actions of GR89696, a highly potent and selective κ-opioid receptor agonist. Br.J.Pharmacol. 103 1819. PMID: 1657267. |