货号 | 4011/50 |
别名 | 4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-te |
供应商 | Tocris |
生物活性 | Photostable synthetic retinoid; analog of ATRA (Cat. No. 0695). Displays similar activity to ATRA when tested on the embryonal carcinoma stem cell model TERA2.cl.SP12. Potently induces neural differentiation in human pluripotent embryonic stem cells. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 332.44 |
分子式 | C23H24O2 |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
CAS号 | 104561-41-3 |
参考文献 | Barnardet al (2009) Synthetic retinoids: structure-activity relationships. Chemistry 15 11430. PMID: 19821467. Maltmanet al (2009) Proteomic profiling of the stem cell response to retinoic acid and synthetic retinoid analogues: identification of major retinoid-inducible proteins. Mol.Biosyst. 5 458. PMID: 19381361. Christieet al (2008) Synthesis and evaluation of synthetic retinoid derivatives as inducers of stem cell differentiation. Org.Biomol.Chem. 6 3497. PMID: 19082150. |