| 货号 | 1643/50 |
| 别名 | (5-Methoxy-1H-indol-2-yl)phenylmeth |
| 供应商 | Tocris |
| 生物活性 | Novel inhibitor of tubulin polymerization; cytotoxic and inhibits tumor cell proliferation in vitro(IC50 = 74 nM). Prevents growth of tumor models in mice following oral administration in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 251.28 |
| 分子式 | C16H13NO2 |
| 可溶性/溶解性 | Soluble to 20 mM in ethanol and to 100 mM in DMSO |
| CAS号 | 74588-78-6 |
| 参考文献 | Beckerset al (2002) 2-aroylindoles, a novel class of potent, orally active small molecule tubulin inhibitors. Cancer Res. 62 3113. PMID: 12036922. Mahboobiet al (2001) Synthetic 2-aroylindole derivatives as a new class of potent tubulin-inhibitory, antimitotic agents. J.Med.Chem. 44 4535. PMID: 11741473. |