| 货号 | 1032/50 |
| 别名 | 1,4-Dihydro-3-(1,2,3,6-tetrahydro-4 |
| 供应商 | Tocris |
| 生物活性 | Potent and highly selective 5-HT1B agonist (Ki values are 8.1, 1100, 1500, 2900 and 7200 nM for 5-HT1B, 5-HT1D, 5-HT1A, 5-HT1c and 5-HT2, respectively). Reduces food intake and decreases body weight in rats. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 288.18 |
| 分子式 | C12H13N3O.2HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 127792-75-0 |
| 参考文献 | Hamidet al (2014) Modulation of neurotransmission by GPCRs is dependent upon the microarchitecture of the primed vesicle complex. J Neurosci. 34 260. PMID: 24381287. Leeet al (1998) Infusion of the serotonin1B(5-HT1B) agonist CP-93,129 into the parabrachial nucleus potently and selectively reduces food intake in rats. Psychopharmacology 136 304. PMID: 9566817. Koeet al (1992) Biochemical and behavioral studies of the 5-HT1B receptor agonist, CP-94,253. Drug Development Research 26241. |