货号 | 0948/50 |
别名 | (R*,R*)-(±)-4-[2-[(2-(3-Chlorophenyl |
供应商 | Tocris |
生物活性 | Potent and selective β3 adrenoceptor agonist (Ki values are 287, 1750 and 1120 nM for β3,β1andβ2 receptors respectively). Also available as part of the β-Adrenoceptor Agonist Tocriset™. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >98 % |
计算分子量 | 385.82 |
分子式 | C19H21NO4ClNa |
可溶性/溶解性 | Soluble to 100 mM in water |
CAS号 | 127299-93-8 |
参考文献 | Boardet al (2000) BRL37344, but not CGP12177, stimulates fuel oxidation by soleus muscle in vitro. Eur.J.Pharmacol. 406 33. PMID: 11011029. Ayo Oriowoet al (1996) The selectivity in vitro of the sterioisomers of the beta-3 adrenoreceptor agonist BRL 37344. J.Pharmacol.Exp.Ther. 277 22. PMID: 8613923. Strosberg and Pietri-Rouxel (1996) Function and regulation of the β3-adrenoceptor. TiPS 17 373. PMID: 8979772. Archet al (1984) Atypical β-adrenoceptor on brown adipocytes as target for anti-obesity drugs. Nature 309 163. PMID: 6325935. |