| 货号 | 1072/50 |
| 别名 | (±)-2-endo-Amino-3-exo-isopropylbicy |
| 供应商 | Tocris |
| 生物活性 | I1 imidazoline binding site selective ligand with a potency at I1 comparable to moxonidine, but devoid of affinity for adrenoceptors and the I2 binding site. Interestingly, in animal models, this compound causes none of the physiological responses associated with the I1 binding site. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 189.73 |
| 分子式 | C10H19N.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 175521-95-6 |
| 参考文献 | Mukaddam-Daheret al (2006) Receptors involved in moxonidine-stimulated strial natriuretic peptide released from isolated normotensive rat hearts. Eur.J.Pharmacol. 541 73. PMID: 16774751. Raaschet al (2002) Agmatine, an endogenous ligand at imidazoline binding sites, does not antagonize the clonidine-mediated blood pressure reaction. Br.J.Pharmacol. 135 663. PMID: 11834614. Munket al (1996) Synthesis and pharmacologic evaluation of 2-endo-amino-3-exo-isopropylbicyclo[2.2.1]heptane: a potent imidazoline1 receptor specific agent. J.Med.Chem. 39 1193. PMID: 8632424. |