TCS PrP Inhibitor 13 (50 MG)
货号：
3238/50 基本售价：
9359.3 元 规格：
50 mg
产品信息
概述| 货号 | 3238/50 |
| 别名 | 2,4-Dihydro-5-(4-nitrophenyl)-2-phenyl-3H-pyrazol-3-one |
性能| 供应商 | Tocris |
| 生物活性 | Antiprion agent. Potently inhibits protease-resistant prion protein (PrP-res) accumulation in two types of prion-infected mouse neuroblastoma (N2a) cell lines (IC50 = 3 nM). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 281.27 |
| 分子式 | C15H11N3O3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 25 mM in ethanol |
| CAS号 | 34320-83-7 |
| 参考文献 | Kimataet al (2007) New series of antiprion compounds: pyrazolone derivatives have potent activity of inhibiting protease-resistant prion protein accumulation. J.Med.Chem. 50 5053. PMID: 17850126. |
