TCS 359 (50 MG)
货号：
2591/50 基本售价：
9359.3 元 规格：
50 mg
产品信息
概述| 货号 | 2591/50 |
| 别名 | 2-[(3,4-Dimethoxybenzoyl)amino]-4,5,6,7-benzo[b]thiophene-3-carboxamide |
性能| 供应商 | Tocris |
| 生物活性 | Potent inhibitor of FLT3 receptor tyrosine kinase (IC50 = 42 nM) that displays selectivity over a range of other kinases. Exhibits antiproliferative effects on MV4-11 cells, a human acute myelogenous leukemia cell line expressing a constitutively active mutant FLT3 (IC50 = 340 nM). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 360.43 |
| 分子式 | C18H20N2O4S |
| 可溶性/溶解性 | Soluble to 30 mM in DMSO |
| CAS号 | 301305-73-7 |
| 参考文献 | Patchet al (2006) Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3. Bioorg.Med.Chem.Lett. 16 3282. PMID: 16580199. |
