| 货号 | 4874/50 |
| 别名 | N-[4-[2,2,2-Trifluoro-1-hydroxy-1-( |
| 供应商 | Tocris |
| 生物活性 | Agonist of retinoic acid receptor-related orphan receptors (ROR) RORα/γ. Increases transcription of RORα target genes; thought to increase p53 stability. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 431.25 |
| 分子式 | C17H10F9NO2< |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Wanget al (2012) Regulation of p53 stability and apoptosis by a ROR agonist. PLoS One 7 e34921. PMID: 22509368. Wanget al (2010) Identification of a synthetic agonist for the orphan nuclear receptors RORα and RORγ, SR1078. ACS Chem.Biol. 5 1029. PMID: 20735016. . |