| 货号 | 2303/50 |
| 别名 | N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl- |
| 供应商 | Tocris |
| 生物活性 | Highly selective α7 nAChR agonist (Ki = 26 nM) displaying negligible blockade of α1β1γδandα3β4 nAChRs (IC50 ≥ 60 μM). Found to be inactive against a panel of 32 receptors at 1 μM, except 5-HT3 receptors (Ki = 930 nM). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 264.75 |
| 分子式 | C14H17ClN2O |
| 可溶性/溶解性 | Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO |
| CAS号 | 123464-89-1 |
| 参考文献 | Bodnaret al (2005) Discovery and structure-activity relationship of quinuclidine benzamides as agonists of α7 nicotinic acetylcholine receptors. J.Med.Chem. 48 905. PMID: 15715459. Haj |