KM 11060 (50 MG)
货号:
3143/50 基本售价:
9359.3 元 规格:
50 mg
产品信息
概述货号 | 3143/50 |
别名 | 7-Chloro-4-[4-[4-chlorophenyl)sulfonyl]-1-piperazinyl]quinoline |
性能供应商 | Tocris |
生物活性 | Corrects F508del-CFTR trafficking; increases the amount of functional CFTR at the plasma membrane (~75%). Shown to inhibit PDE5 activity. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >98 % |
计算分子量 | 422.33 |
分子式 | C19H17Cl2N3O2S |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
CAS号 | 774549-97-2 |
参考文献 | Robertet al (2008) Structural analog of Sildenafil identified as a novel corrector of the F508del-CFTR trafficking defect. Mol.Pharmacol. 73 478. PMID: 17975008. |