K 858 (50 MG)
货号：
3703/50 基本售价：
9359.3 元 规格：
50 mg
产品信息
概述| 货号 | 3703/50 |
| 别名 | N-(4-Acetyl-4,5-dihydro-5-methyl-5-phenyl-1,3,4-thiadiazol-2-yl)acetamide |
性能| 供应商 | Tocris |
| 生物活性 | Selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor (IC50 = 1.3 μM). Induces mitotic arrest, caspase-3 activation and cell growth inhibition in HCT116 cells. Displays no effect on microtubule dynamics. Preferentially induces mitotic arrest in cancer cells. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 277.34 |
| 分子式 | C13H15N3O2S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
| CAS号 | 72926-24-0 |
| 参考文献 | Nakaiet al (2009) K858, a novel inhibitor of mitotic kinesin Eg5 and antitumor agent, induces cell death in cancer cells. Cancer Res. 69 3901. PMID: 19351824. |
