| 货号 | 3780/50 |
| 别名 | 2-[[[4-(4-Fluorophenoxy)phenyl]sulf |
| 供应商 | Tocris |
| 生物活性 | Broad spectrum MMP inhibitor (IC50 values are 0.7, 0.9, 13, 16 and 1170 nM for MMP-2, MMP-13, MMP-9, MMP-3 and MMP-1 respectively). Attenuates early left ventricular dilation after experimental myocardial infarction in mice. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >97 % |
| 计算分子量 | 368.38 |
| 分子式 | C16H16FN2O5S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 210755-45-6 |
| 参考文献 | Fanget al (2007) Differences in inflammation, MMP activation and collagen damage account for gender difference in murine cardiac rupture following myocardial infarction. J.Mol.Cell.Cardiol. 43 535. PMID: 17689559. Lindseyet al (2002) Selective matrix metalloproteinase inhibition reduces left ventricular remodeling but does not inhibit angiogenesis after myocardial infarction. Circulation 105 753. PMID: 11839633. Rohdeet al (1999) Matrix metalloproteinease inhibition attenuates early left ventricular enlargement after experimental myocardial infarction in mice. Circulation 99 3063. PMID: 10368126. |