Aureothricin
货号：
19942-5mg 基本售价：
8862.0 元 规格：
5 mg
产品信息
概述| 货号 | 19942-5mg |
| 描述 | Aureothricin is a dithiolopyrrolone antibiotic first isolated from Streptomyces sp. that exhibits broad-spectrum antimicrobial activity against many Gram-positive and Gram-negative bacteria, as well as strains of M. tuberculosis.1 It is also reported to inhibit tumor angiogenesis, blocking activity of the vitronectin receptor integrin αvβ3 with an IC50 value of 1.1 µM.2 |
| 别名 | Farcinicin;Propionylpyrrothione; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Li, B.,Wever, W.J.,Walsh, C.T., et al. Dithiolopyrrolones: Biosynthesis, synthesis, and activity of a unique class of disulfide-containing antibiotics. Natural Product Reports 31(7), 905-923 (2014).
2.Minamiguchi, K.,Kumagai, H.,Masuda, T., et al. Thiolutin, an inhibitor of HUVEC adhesion to vitronectin, reduces paxillin in HUVECs and suppresses tumor cell-induced angiogenesis. International Journal of Cancer 93(3), 307-316 (2001).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 242.3 |
| 分子式 | C9H10N2O2S2 |
| CAS号 | 574-95-8 |
| 稳定性 | ≥ 1 year |
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