Bafilomycin C1
货号：
19625-5mg 基本售价：
8764.0 元 规格：
5 mg
产品信息
概述| 货号 | 19625-5mg |
| 描述 | Bafilomycin C1 is a selective, reversible inhibitor of vacuolar H+-ATPases (V-ATPases).1 It blocks these pumps in mammalian, plant, or fungal cells, preventing proton transport and compartment acidification.1 Bafilomycin C1 has been shown to have angiostatic activity in the chick chorioallantoic membrane assay.2 It has also been used, when coupled to cellulose, to purify V-ATPases.3 |
| 别名 | 2-Demethyl-2-methoxy-24-methyl-hygrolidin;L-681,110A1; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Bowman, E.J.,Siebers, A., and Altendorf, K. Bafilomycins: A class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells. Proceedings of the National Academy of Sciences of the United States of America 85, 7972-7976 (1988).
2.Ishii, T.,Hida, T.,Iinuma, S., et al. TAN-1323 C and D, new concanamycin-group antibiotics; detection of the angiostatic activity with a wide range of macrolide antibiotics. J.Antibiot.(Tokyo) 48(1), 12-20 (1995).
3.Rautiala, T.J.,Koskinen, A.M., and Väänänen, H.J. Purification of vacuolar ATPase with bafilomycin C1 affinity chromatography. Biochem.Bioph.Res.Commun. 194(1), 50-56 (1993).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 720.9 |
| 分子式 | C39H60O12 |
| CAS号 | 88979-61-7 |
| 稳定性 | ≥ 2 years |
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