| 货号 | 0532/50 |
| 别名 | Hexamethylene-bis-[dimethyl-(3-phth |
| 供应商 | Tocris |
| 生物活性 | Stabilizes cholinergic antagonist-receptor complexes by an allosteric effect. Increases the protective effect of atropine against organophosphate poisoning. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 708.53 |
| 分子式 | C32H44Br2N4O4 |
| 可溶性/溶解性 | Soluble to 10 mM in DMSO |
| CAS号 | 21093-51-6 |
| 参考文献 | Mohret al (1992) Equipotent allosteric effect of W84 on [3H]-NMS binding to cardiac muscarinic receptors from guinea-pig, rat and pig. Pharmacol.Toxicol. 70 198. PMID: 1579545. Jepsenet al (1988) Allosteric stabilisation of [3H]-N-methylscopolamine binding in guinea pig myocardium by an antidote against organophosphate intoxication. Pharmacol.Toxicol. 63 163. PMID: 3054859. Mitchelson (1975) Antimuscarinic action of an alkane-bis ammonium compound alone and in combination with (+)-bensetimide. Eur.J.Pharmacol. 33 237. PMID: 1242377. |