货号 | 1435/50 |
别名 | 9-(Tetrahydro-2-furanyl)-9H-purin-6 |
供应商 | Tocris |
生物活性 | Inhibitor of adenylyl cyclase (IC50 = 1.4 μM). Inhibits PGE1-stimulated increases in cAMP levels in intact human platelets. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 205.22 |
分子式 | C9H11N5O |
可溶性/溶解性 | Soluble to 50 mM in DMSO |
CAS号 | 17318-31-9 |
参考文献 | Houraniet al (2001) Role of cyclic nucleotides in vasodilations of the rat thoracic aorta induced by adenosine analogues. Br.J.Pharmacol. 133 833. PMID: 11454656. Fabbriet al (1991) Inhibition of adenylate cyclase of catfish and rat hepatocyte membranes by 9-(tetrahydro-2-furyl)adenine (SQ 22536). J.Enzyme Inhib. 5 87. PMID: 1669444. Harriset al (1979) Inhibition of adenylate cyclase in human blood platelets by 9-substituted adenine derivatives. J.Cyclic Nucleotide Res. 5 125. PMID: 221552. |