SMANT hydrochloride (50 MG)
货号：
4662/50 基本售价：
8704.9 元 规格：
50 mg
产品信息
概述| 货号 | 4662/50 |
| 别名 | N-(4-Bromophenyl)-3,5-dimethyl-1-piperidinepropanamide hydrochloride |
性能| 供应商 | Tocris |
| 生物活性 | Inhibitor of Smoothened (Smo) signaling via a unique mechanism. Inhibits Shh-induced accumulation of Smo::EGFP fusion protein in the primary cilium (IC50 = 1.1 μM). Inhibits both wild-type Smo and an oncogenic form (SmoM2) with similar efficacy. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 375.73 |
| 分子式 | C16H23BrN2O.HCl |
| 可溶性/溶解性 | Soluble to 20 mM in water and to 100 mM in DMSO |
| 参考文献 | Wanget al (2012) Selective identification of Hedgehog pathway antagonists by direct analysis of Smoothened ciliary translocation. ACS Chem.Biol. 7 1040. PMID: 22554036. |
