| 货号 | 0987/50 |
| 别名 | (8aR,12aS,13aS)-5,8,8a,9,10,11,12,1 |
| 供应商 | Tocris |
| 生物活性 | α2-adrenoreceptor antagonist (Kd values are; 0.18, 0.19 and 0.42 nM for α2Bα2Candα2A, respectively in rat). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 400.96 |
| 分子式 | C19H28N2O3S.HCl |
| 可溶性/溶解性 | Soluble to 25 mM in water |
| CAS号 | 158854-42-3 |
| 参考文献 | Uhlenet al (1998) [3H]RS79948-197 binding to rat, guinea pig and pig α2A-, α2B and α2C-adrenoceptors. Comparison with MK912, RX821002, rauwolscine and yohimbine. Eur.J.Pharmacol. 343 93. PMID: 9551719. Humeet al (1996) Evaluation in rat of RS-79948-197 as a potential PET ligand for central α2-adrenoceptors. Eur.J.Pharmacol. 317 67. PMID: 8982721. Clarket al (1989) (8aα,12aα,13aα)-5,8,8a,9,10,11,12,12a,13,13a-Decahydro-3-methoxy-12-(ethylsulphonyl)-6H-isoquino[2,1-g][1,6]-naphthyridine, a potent and highly selective α2-adrenoceptor antagonist. J. Med. Chem. 32 2034. PMID: 2570150. |