NS 3861 (50 MG)
货号：
4831/50 基本售价：
8704.9 元 规格：
50 mg
产品信息
概述| 货号 | 4831/50 |
| 别名 | 3-(3-Bromo-2-thienyl)-8-methyl-8-azabicyclo[3.2.1]oct-2-ene fumarate |
性能| 供应商 | Tocris |
| 生物活性 | α3β2 full agonist (EC50 = 1.6 μM). Also α3β4 partial agonist (EC50 = 1 μM). Exhibits minimal activity at α4β2 and α4β4. Displays high affinity for α3β4,α4β4,α3β2 and α4β2 (Ki values are 0.62, 7.8, 25 and 55 nM respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 400.29 |
| 分子式 | C12H14BrNS.C4H |
| 可溶性/溶解性 | Soluble to 50 mM in water and to 100 mM in DMSO |
| 参考文献 | Harpsøeet al (2013) Molecular determinants of subtype-selective efficacies of cytisine and the novel compound NS3861 at heteromeric nicotinic acetylcholine receptors. J.Biol.Chem. 288 2559. PMID: 23229547. |
