| 货号 | 2995/50 |
| 别名 | N-(5-Chloro-2-hydroxyphenyl)-N'-[2-c |
| 供应商 | Tocris |
| 生物活性 | Selective positive allosteric modulator of α7 nicotinic acetylcholine receptors. Exhibits no substantial activity for α4β2,α3β3 and α1-containing receptors. Displays cognitive-enhancing properties in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 365.13 |
| 分子式 | C14H9Cl2F3N2O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| CAS号 | 501684-93-1 |
| 参考文献 | Freitaset al (2013) The antinociceptive effects of nicotinic receptors α7-positive allosteric modulators in murine acute and tonic pain models. J.Pharmacol.Exp.Ther. 344 264. PMID: 23115222. Timmermannet al (2007) An allosteric modulator of the α7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo. J.Pharmacol.Exp.Ther. 323 294. PMID: 17625074. |