| 货号 | 0468/50 |
| 别名 | N,N'-bis[3-(Ethylamino)propyl]-1,3-p |
| 供应商 | Tocris |
| 生物活性 | Highly potent inducer of spermidine/spermine N1-acetyltransferase, able to increase enzyme activity 200-1000 fold. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 390.27 |
| 分子式 | C13H32N4.4HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 121749-39-1 |
| 参考文献 | Fogel-Petrovicet al (1997) Structural basis for differential induction of spermidine/spermine N1-acetyltransferase activity by novel spermine analogs. Mol.Pharmacol. 52 69. PMID: 9224814. Porteret al (1993) Antitumour activity of N1,N12-bis(ethyl)-norspermine against human melanoma xenografts and possible biochemical correlates of drug action. Cancer Res. 53 581. PMID: 8425191. Bernackiet al (1992) Antitumour activity of N1,N12-bis(ethyl)spermine homologs against human MALME-3 melanoma xenografts. Cancer Res. 52 2424. PMID: 1568212. Libbyet al (1991) Characterization of human spermidine spermine N1-acetyltransferase purified from cultured melanoma cells. Arch.Biochem.Biophys. 284 238. PMID: 1989509. |