货号 | 0907/50 |
别名 | 7-Chloro-4-hydroxy-3-(3-phenoxy)phe |
供应商 | Tocris |
生物活性 | An orally active and long acting anticonvulsant with high affinity and selectivity for the glycine site on the NMDA receptor. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 363.8 |
分子式 | C21H14CINO3 |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
CAS号 | 142326-59-8 |
参考文献 | Bristowet al (1996) The atypical neuroleptic profile of the glycine/N-methyl-D-aspartate receptor antagonist, L-701,324 in rodents. J.Pharmacol.Exp.Ther. 277 578. PMID: 8627534. Bristowet al (1996) Anticonvulsant and behavioral profile of L-701,324, a potent, orally active antagonist at the glycine modulatory site on the N-methyl-D-aspartate receptor complex. J.Pharmacol.Exp.Ther. 279 492. PMID: 8930150. Obrenovitch and Zilkha (1996) Inhibition of cortical spreading depression by L-701,324, a novel antagonist at the glycine site of the N-methyl-D-aspartate receptor complex. Br.J.Pharmacol. 117 931. PMID: 8851513. Kulagowskiet al (1994) 3'-(Arylmethyl)- and 3'-(aryloxy)-3-phenyl-4-hydroxyquinolin-2(1H)-ones: orally active antagonists of the glycine site on the NMDA receptor. J.Med.Chem. 37 1402. PMID: 8182696. |