货号 | 0705/50 |
别名 | 7-Chloro-3-(cyclopropylcarbonyl)-4- |
供应商 | Tocris |
生物活性 | An antagonist at the glycine-NMDA site (IC50 = 420 nM). Also a potent systemic anticonvulsant. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 263.68 |
分子式 | C13H10ClNO3 |
可溶性/溶解性 | Soluble to 50 mM in DMSO |
CAS号 | 151057-13-5 |
参考文献 | Stone (2000) Development and therapeutic potential of kynurenic acid and kynurenine derivatives for neuroprotection. TiPS 21 149. PMID: 10740291. Rowleyet al (1993) 3-Acyl-4-hydroxyquinolin-2(1H)-ones. Systemically active anticonvulsants acting by antagonism at the glycine site of the NMDA receptor complex. J.Med.Chem. 36 3386. PMID: 8230129. |