| 货号 | 1448/50 |
| 别名 | (±)-(R,R)-N-[2-Hydroxy-5-[1-hydroxy- |
| 供应商 | Tocris |
| 生物活性 | Potent, selective and long-acting β2-adrenoceptor agonist. Displays 330-fold selectivity for β2overβ1 receptors (pKd values are 8.12 and 5.58 respectively). Potently relaxes guinea pig trachea (pD2 = 9.29), and is longer-acting and 100-fold more potent than salbutamol. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 402.45 |
| 分子式 | C19H24N2O4.紺4H4O4 |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO |
| CAS号 | 183814-30-4 |
| 参考文献 | Nalineet al (1994) Relaxant effects and durations of action of formoterol and salmeterol on the isolated human bronchus. Eur.Respir.J. 7 914. PMID: 7914176. Anderson (1993) Formoterol: pharmacology, molecular basis of agonism, and mechanism of long duration of a highly potent and selective β2-adrenoceptor agonist bronchodilator. Life Sci. 52 2145. PMID: 8099696. Deckeret al (1982) Effects of N-aralkyl substitution of β-agonists on α- and β-adrenoceptor subtypes: pharmacological studies and binding assays. J.Pharm.Pharmacol. 34 107. PMID: 6121868. |