货号 | 1396/50 |
别名 | N-(4-Hydroxyphenyl)retinamide; 4-HPR |
供应商 | Tocris |
生物活性 | Synthetic retinoid agonist. Antiproliferative, antioxidant and anticancer agent with a long half-life in vivo. Apoptotic effects appear to be mediated by a mechanism distinct from that of 'classical' retinoids. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 391.55 |
分子式 | C26H33NO2 |
可溶性/溶解性 | Soluble to 100 mM in ethanol and to 100 mM in DMSO |
CAS号 | 65646-68-6 |
参考文献 | Le Dozeet al (2000) Pharmacokinetics of all-trans retinoic acid, 13-cis retinoic acid, and fenretinide in plasma and brain of rat. Drug Metab.Dispos. 28 205. PMID: 10640519. Takahashi (2000) Antioxidant properties of N-(4-hydroxyphenyl)retinamide (fenretinide). Biol.Pharm.Bull. 23 222. PMID: 10706389. Ulukaya and Wood (1999) Fenretinide and its relation to cancer. Cancer Treat.Rev. 25 229. PMID: 10448131. |