| 货号 | 2645/50 |
| 别名 | N-[[(3R)-1-(Aminoiminomethyl)-3-pip |
| 供应商 | Tocris |
| 生物活性 | Competitive reversible inhibitor of interleukin-2 (IL-2) binding to its receptor (IC50 = 3 μM for inhibition of IL-2 interaction with IL-2R α-subunit). Appears to compete with IL-2Rα for its binding site on IL-2. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 560.57 |
| 分子式 | C23H24FN3O2S |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO and to 5 mM in ethanol |
| CAS号 | 127625-29-0 |
| 参考文献 | Braistedet al (2003) Discovery of a potent small molecule IL-2 inhibitor through fragment assembly. J.Am.Chem.Soc. 125 3714. PMID: 12656598. Tilleyet al (1997) Identification of a small molecule inhibitor of the IL-2/IL-2Rα receptor interaction which binds to IL-2. J.Am.Chem.Soc. 1197589. |