EMD 386088 hydrochloride (50 MG)
货号：
2382/50 基本售价：
8704.9 元 规格：
50 mg
产品信息
概述| 货号 | 2382/50 |
| 别名 | 5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole hydrochloride |
性能| 供应商 | Tocris |
| 生物活性 | Potent 5-HT6 receptor agonist (EC50= 1.0 nM) that displays selectivity over other 5-HT receptors (IC50 values are 7.4, 110, 180, 240, 450, 620, 660 and 3000 nM for 5-HT6, 5-HT1D, 5-HT1B, 5-HT2A, 5-HT2C, 5-HT4, 5-HT1A and 5-HT7 receptors respectively). Shows moderate affinity at 5-HT3 receptors (IC50 = 34 nM). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 283.2 |
| 分子式 | C14H15N2Cl.HCl |
| 可溶性/溶解性 | Soluble to 25 mM in water and to 100 mM in DMSO |
| CAS号 | 54635-62-0 |
| 参考文献 | Mattssonet al (2005) 2-Alkyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as novel 5-HT6 receptor agonists. Bioorg.Med.Chem.Lett. 15 4230. PMID: 16055331. |
