| 货号 | 2632/50 |
| 别名 | N-[4-(4-Morpholinyl)butyl]-2-benzof |
| 供应商 | Tocris |
| 生物活性 | Selective inhibitor of MMP-13 (89% inhibition at 10 μg/mL) that displays no activity at MMP-1, MMP-9 or TACE. Inhibits in vitro invasion by the human pituitary adenoma cell line HP75. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 338.83 |
| 分子式 | C17H33N2O3.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 75 mM in DMSO |
| CAS号 | 307002-71-7 |
| 参考文献 | Borget al (2003) IL1 alpha, IL6 and MMP13 are required for invasion by the human pituitary cell line HP75. Endocrine Abstr. 5122. Chenet al (2000) Structure-based design of a novel, potent, and selective inhibitor for MMP-13 utilizing NMR spectroscopy and computer-aided molecular design. J.Am.Chem.Soc. 1229648. |