CGH 2466 dihydrochloride (50 MG)
货号：
2344/50 基本售价：
8704.9 元 规格：
50 mg
产品信息
概述| 货号 | 2344/50 |
| 别名 | 4-(3,4-Dichlorophenyl)-5-(4-pyridinyl)-2-thiazolamine dihydrochloride |
性能| 供应商 | Tocris |
| 生物活性 | Adenosine A1, A2B and A3 receptor antagonist (IC50 values are 19, 21, and 80 nM respectively). Also inhibits p38 MAPK (IC50 = 187 - 400 nM) and phosphodiesterase type 4D (IC50 = 22 nM). Displays potent anti-inflammatory effects in vitroandin vivo. Potentially useful for asthma and chronic obstructive pulmonary disease (COPD) research. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 395.13 |
| 分子式 | C14H9N3SCl2.2HCl |
| 可溶性/溶解性 | Soluble to 10 mM in DMSO with gentle warming and to 5 mM in ethanol |
| CAS号 | 252198-68-8 |
| 参考文献 | Trifilieffet al (2005) CGH2466, a combined adenosine receptor antagonist, p38 mitogen-activated protein kinase and phosphodiesterase type 4 inhibitor with potent in vitroandin vivo anti-inflammatory activities. Br.J.Pharmacol. 144 1002. PMID: 15685201. |
