| 货号 | 0744/50 |
| 别名 | N-Acetylsphingosine |
| 供应商 | Tocris |
| 生物活性 | A potent modulator of cell proliferation and differentiation. Activates protein phosphatase-1 (PP1) and -2A (PP2A), as well as ceramide-activated protein phosphatase (CAPP) in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 341.53 |
| 分子式 | C20H39NO3 |
| 可溶性/溶解性 | Soluble to 100 mM in ethanol and to 100 mM in DMSO |
| CAS号 | 3102-57-6 |
| 参考文献 | Xie and Johnson (1997) Ceramide selectively decreases tau levels in differentiated PC12 cells through modulation of calpain I. J.Neurochem. 69 1020. PMID: 9282924. Quintanset al (1994) Ceramide mediates the apoptotic response of WEHI 231 cells to anti-immunoglobulin, corticosteroids and irradiation. Biochem.Biophys.Res.Commun. 202 710. PMID: 8048941. Dobowsky and Hannun (1992) Ceramide stimulates a cytosolic protein phosphatase. J.Biol.Chem. 267 5048. PMID: 1312082. Kimet al (1991) Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor α and γ-interferon. J.Biol.Chem. 266 484. PMID: 1845977. |