| 货号 | 0511/50 |
| 别名 | N-[2-(3,4-Dichlorophenyl)ethyl]-N-m |
| 供应商 | Tocris |
| 生物活性 | Potent and selective σ-ligand (Ki against [3H]-(+)-3-PPP = 0.34 nM). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 463.08 |
| 分子式 | C15H22Cl2N2.2HBr |
| 可溶性/溶解性 | Soluble to 50 mM in water |
| CAS号 | 138356-08-8 |
| 参考文献 | Whittemoreet al (1997) Antagonism of N-methyl-D-aspartate receptors by σ site ligands: potency, subtype-selectivity and mechanisms of inhibition. J.Pharmacol.Exp.Ther. 282 326. PMID: 9223571. Monnetet al (1996) Differentiation of σ ligand-activated receptor subtypes that modulate NMDA-evoked [3H]-noradrenaline release in rat hippocampal slices. Br.J.Pharmacol. 119 65. PMID: 8872358. De Costaet al (1992) Synthesis, characterization, and biological evaluation of a novel class of N-(arylethyl)-N-alkyl-2-(1-pyrrolidinyl)ethylamines - structural requirements and binding affinity at the σ receptor. J.Med.Chem. 35 38. PMID: 1310114. |