货号 | 2673/50 |
别名 | O-4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5 |
供应商 | Tocris |
生物活性 | Inhibitor of intestinal α-glucosidase (IC50 = 11 nM). Antidiabetic; inhibits the hydrolysis of complex carbohydrates. |
运输条件 | Ambient |
存放说明 | Ambient |
计算分子量 | 645.25 |
分子式 | C25H43NO18 |
可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
CAS号 | 56180-94-0 |
参考文献 | Okiet al (2000) Evaluation of alpha-glucosidase inhibition by using an immobilized assay system. Biol.Pharm.Bull. 23 1084. PMID: 10993209. Balfour and McTavish (1993) Acarbose: an update of its pharmacology and therapeutic use in diabetes mellitus. Drugs 46 1025. PMID: 7510610. Krauseet al (1982) Inhibition of disaccharide digestion in rat intestine by the alpha-glucosidase inhibitor acarbose (BAY g 5421). Digestion 23 232. PMID: 6754513. |