| 货号 | 3025/50 |
| 别名 | 7-(3,5,6-Trimethyl-1,4-benzoquinon- |
| 供应商 | Tocris |
| 生物活性 | Thromboxane A2 (TP) receptor antagonist. Antiasthmatic agent; inhibits platelet aggregation and bronchoconstriction induced by a TXA2 mimetic in guinea pigs. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 354.44 |
| 分子式 | C22H26O4 |
| 可溶性/溶解性 | Soluble to 75 mM in 1.1eq. NaOH and to 100 mM in DMSO |
| CAS号 | 112665-43-7 |
| 参考文献 | Cuiet al (2007) Leukotrienes and cyclooxygenase products mediate anaphylactic venoconstriction in ovalbumin sensitized rat livers. Eur.J.Pharmacol. 576 99. PMID: 17706964. Kurokawaet al (1994) Antagonism of the human thromboxane A2 receptor by an anti-asthmatic agent AA-2414. Biol.Pharm.Bull. 17 383. PMID: 8019502. Ashidaet al (1989) A novel anti-asthmatic quinone derivative, AA-2414 with a potent antagonistic activity against a variety of spasmogenic prostanoids. Prostaglandins 38 91. PMID: 2748922. |