货号 | 0666/50 |
别名 | 3-(4-Allylpiperazin-1-yl)-2-quinoxa |
供应商 | Tocris |
生物活性 | A competitive 5-HT3 antagonist, almost 100 times more potent than tropisetron, but with widely differing activity in various tissues. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 395.42 |
分子式 | C16H17N5.C4H4O4 |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
参考文献 | Buznikovet al (2005) The pre-nervous serotonergic system of developing sea urchin embryos and larvae: pharmacologic and immunocytochemical evidence. Neurochem.Res. 30 825. PMID: 16187217. Durket al (2005) 5-Hydroxytryptamine modulates cytokine and chemokine production in LPS-primed human monocytes via stimulation of different 5-HTR subtypes. Int.Immunol. 17 599. PMID: 15802305. Mongeet al (1993) Novel antagonists of 5-HT3 receptors. Synthesis and biological evaluation of piperazinylquinoxaline derivatives. J.Med.Chem. 36 2745. PMID: 8410988. |