| 货号 | 0782/50 |
| 别名 | 2-Chloro-11-(4-methylpiperazino)dib |
| 供应商 | Tocris |
| 生物活性 | Dopamine D2-like receptor antagonist that displays some selectivity for D4 receptors (Ki values are 0.54 and 2.5 nM for D4 and D2 receptors respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 442.9 |
| 分子式 | C19H19ClN2O.C4H4O4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Zawilskaet al (2003) L-745,870 suppresses the nighttime serotonin N-acetyltransferase activity in chick retina: in vivo evidence for agonist activity at D4-dopamine receptors. J.Neural Transm. 110 219. PMID: 12658371. Phillipset al (1995) Binding of 5H-dibenzo[a,d]cycloheptane and dibenz[b,f]oxapin analogues of clozapine to dopamine and serotonin receptors. J.Med.Chem. 38 708. PMID: 7861418. Phillipset al (1994) Binding of 5H-dibenzo[b,e][1,4]diazepine and chiral 5H-dibenzo[a,d]cycloheptane analogues of clozapine to dopamine and serotonin receptors. J.Med.Chem. 37 2686. PMID: 8064797. |